Viagra was the first oral drug for ED (stands for erectile dysfunction), but very soon it got several competitors — Cialis, Stendra, Levitra, etc. We have not had the last one in our catalog since 2018, as well as any other preparations based on Vardenafil.

These medications have a similar principle of action, they inhibit the performance of the endogenous compound phosphodiesterase type 5 (PDE5 for shortness). In a normal situation, this bioactive chemical degrades the nucleotide with a long name “cyclic guanosine monophosphate”, or simply cGMP, which in turn is required to relax the muscles in the penis vessels and let the blood flow into the erectile tissues.

When men are sexually stimulated, their bodies release cGMP and they have an erection. When the arousal wanes, PDE5 breaks down cGMP, and boners fall flat. The biochemical disbalance leads to impotence. In 70% of ED cases Viagra successfully cures the malady, and these figures show that PDE5 inhibitors are the most effective treatment for erectile dysfunction so far. Other approved uses of such drugs are pulmonary hypertension and prostate enlargement.

There is no reason to include yourself within those remaining unlucky 30% in case you have no boner after you’ve used the pill for the first time. The best thing to do is to consult a doctor, tell them about the situation, and let him look through the entire medical record. Oftentimes, the solution is plain to see, and the tablets start working after a patient has some tests done and additional measures taken. We also have several recommendations for men with sexual maladies, hopeful they can help them regain a happy and harmonious intimate life.

Don’t Forget to Get Excited

You remember, we told you that the biochemical reactions that lead to erection do not start before a man is sexually stimulated. PDE5 inhibitors do not make the penis hard magically, instead they aid the healthy performance of male bodies. Their active compounds, namely sildenafil for Viagra and tadalafil for Cialis, substitute for cGMP, thus increasing blood circulation in the penis. However, there won’t be any cGMP in the vessels without sexual excitement. Hence, Viagra will stay ineffective, too.

So, to make it work, you need some stimulation. It can be either physical or emotional, so you can watch some erotic movie or engage in foreplay with your girlfriend. In fact, this is one of the advantages of Viagra et al. These tablets will not put you to shame because of an unexpected boner in the wrong place and at the wrong time. They work exclusively when needed, and their action wanes together with the sexual excitement. Thus, you always know what to expect from your penis after the tablet, and there won’t be any surprises.

Refuse to Eat Before Taking ED Tablets

Another popular mistake is administering the drugs immediately after or shortly before a nice substantial dinner. Yes, manufacturers claim that Viagra and Cialis are effective with or without food. In practice, fatty meals decrease the absorption of the blue pills. A man may get only a half-dose effect if he takes sildenafil citrate on a full stomach. Moreover, this also significantly delays the onset of action. Grapefruits, alcohol, and cigarettes alter the performance of the drug in your organism, too. They can make it less effective or postpone its actions.

Cialis is thought to be less dependent on food, but still some users claim that it works better at least two hours after a meal. As for liquors, smoking, and sour juices, it is best to avoid them when taking tadalafil. Anyway, when you know these simple rules, it is easy to plan your intimate life according to your eating schedule. It does not mean, though, that the ED pill will necessarily give no effect after a heavy dinner. We just want to tell all men that if something is not working right now — maybe, all you need to do is change your eating habits.

Wait an Hour for the Best Results

Obviously, patients with erectile problems can no longer have as spontaneous of a sex life as they had before the illness. Many men think that the tablet works like a race car — just step on the gas and rush towards the bedroom right away! They do not get any help like that from Viagra or Cialis, and make the assumption that these pills are useless. We have good advice for such nimble guys — give your pill some time to go to your stomach, get digested, and absorb into the bloodstream, and only then will it produce its effects.

The information in the package leaflets says that Viagra starts working 30 minutes after consumption. Cialis is a little bit slower, and it may need up to 120 minutes to reach the peak plasma level. Yes, various publications on the net get hopes up that sildenafil provides an erection a little more than 10 minutes after intake. In individual cases, tadalafil may show effectiveness in a quarter of an hour. When you are not one of those cases, there is no need to give up using the pills. The best way to take any drugs for erection is to give them some time to get started and only then romp in the bed.

Try One Dosage at Least Several Times

At the very beginning of the history of ED oral drugs, there was a common practice in cases when the medications were not effective. A doctor prescribed two intakes of the minimum dose of the PDE5 inhibitor, then increased it and tried it twice, and finally the patient was administered two pills with the maximum strength. Thus, each patient tried the same drug six times in a row before the health adviser decided to change the treatment. Nowadays, this strategy is not that popular because men rarely start with the lowest strength.

According to a recent study, one third of men who fail with the first ED tablet do not try it for a second time. Remembering that the effectiveness of PDE5 inhibitors is very sensitive to several factors, this is not the right decision. In order to rule out any chances that the drug doesn’t work due to a greasy dinner or bad mood, every ED patient should try one dosage at least several times. For instance, those who prefer Viagra should start with 50 mg and try it twice or thrice. Then use 100 mg several times, and only if it does not work, can 200 mg be considered to take for best results. The strength of Cialis pills varies from 2.5 mg to 60 mg, but most doctors prescribe between 5 mg to 20 mg. The lowest dose was approved for daily use in 2009.

Increase Dosage Only After Visit a Doctor

This brings us to the next problem — when a patient can increase the dosage. The best and the only correct answer for this question is as follows: only after a doctor’s consultation! Self-medication can be very dangerous, especially with prescription-only meds. You never know the real reason why the pill, which did help yesterday, does not produce any effect anymore. Remember that a stronger tablet can cause dangerous side effects without any significant benefits.

Such cases are not typical, since we have already said, the majority of ED patients are successfully cured with the help of PDE5 inhibitors. Still, before changing anything in your treatment, you should seek professional advice. You may ask what to do when the usual effective dose stops working? Of course, you should not wait too long. If you get no erection three times or more in a row — go to a doctor. The healthcare provider will see your medical record, find out the reason of the drug’s ineffectiveness, and prescribe a new dose or another medication.

Buy Others Erectile Dysfunction Drugs

Based on a study done by Spanish scientists, Dr. Jacob Rajfer from California University says that the main problem of ED patients is the lack of awareness of how the drugs work and their correct administration. The researchers found out that most men who reported the ineffectiveness of PDE5 inhibitors simply did not know how to use them. After they had received all the necessary information, three quarters of them said that they gained back their erections.

Nevertheless, your ED pills may stay useless even after you follow all our recommendations. You should not despair, and remember that despite the fact that PDE5 inhibitors have similar biochemical activity, they are not identical. When Viagra does not help — Cialis or Stendra may bring back your sexual health. In the ViaBestBuy online drugstore we have generic non prescription medications that are chemical twins of Viagra and Cialis. They are much cheaper than the products of Pfizer Inc. and Eli Lilly, but their quality and effectiveness are the same.

Here are some of our bestsellers:

• Viagra 100 mg, if you buy 100 tabs, you pay only $99. As you see, we really save your budget;
• Cialis 20 mg, the most effective and popular dose of the drug. One pill costs less than a dollar;
• Kamagra 100 mg, the tablets with sildenafil citrate, equivalent to Viagra but 20 times cheaper than the branded medicine;
• other alternatives to Viagra and Cialis, e.g. Aurogra Sildenafil 100 mg, Suhagra 100 mg, Cenforce 200 mg, Forzest 20 mg, Zydalis 20 mg, etc.

Other than tablets, we have oral strips, jellies, and chewables. Any client will find an appropriate solution for his sexual problem in the ViaBestBuy pharmacy.